Minato Sahashi, a brilliant but struggling 19-year-old, has failed his college entrance exams for the second time, leading those around him to view him as worthless. Yet, his seemingly bleak future takes a sharp turn when a beautiful, supernatural woman falls from the sky into his life. This woman, Musubi, is a unique entity known as a "Sekirei," a humanoid extraterrestrial possessing extraordinary abilities. These aliens are known to kiss humans who carry the Ashikabi gene in order to awaken additional latent powers deep within them. Seeing potential in the seemingly insignificant youth, Musubi kisses the bewildered Minato, establishing a bond between them. This act pulls him into the high-stakes world of the Sekirei, where he and his new partner must compete against others in a survival battle known as the "Sekirei Plan." However, unknown to the contestants, there is far more at risk than what the competition initially entailed.