Keitarou Gentouga has always drawn spirits because of his potent spiritual aura. A harrowing encounter with one resulted in a curse on his right hand, compelling him to keep it gloved at all times. Now a college freshman, Keitarou strives to lead as ordinary a life as he can. Encouraged by his childhood friend Eiko Houzuki, he takes up work as a private tutor. Being the top student in his cohort, his first assignment is with the tutoring agency's most promising pupil, Yayoi Houzuki. To Keitarou's astonishment, Yayoi is Eiko's cousin and possesses two pupils in each eye, granting her the ability to perceive the spirit world and deliberately hunt vengeful spirits for exorcism. Since a car crash claimed both her parents, Yayoi has been hunting for the powerful spirit that abducted her mother's soul. Noticing how spirits are drawn to Keitarou, she enlists his help to gather other malevolent spirits that will aid her in the coming battle. Though her mission is perilous, Keitarou reluctantly agrees to join her, even as every new spirit they encounter tests his determination.