After finishing the conclusion of her favorite manga series, Fuuko Izumo finally feels prepared to end her life. For the last 10 years, Fuuko has suffered from a condition that brings extreme misfortune to anyone who touches her. This has severely impacted her surroundings, even inadvertently causing the deaths of people around her—including her parents. As she stands on a bridge over train tracks, Fuuko is touched by a strange man, causing the ground beneath him to collapse and drop him in front of an oncoming train. However, when Fuuko finds the man's corpse, she discovers that his body is regenerating and that he is coming back to life. The man, whom Fuuko names Andy, is immortal—and like her, he also wishes for death. Initially dismissive, Fuuko eventually decides to team up with Andy to give him the best death possible; but a mysterious organization lurks in the shadows, hoping to take advantage of the duo's bizarre abilities.