In 1930, vampires have infiltrated Tokyo to feed on its unsuspecting citizens. As the victim count rises, city authorities hire the Jaegers—a strange, diverse group employed by the V Shipping Company to hunt vampires worldwide. Disguising themselves with musical instrument cases, the Jaegers fight the vampires with the same mercilessness shown by their foes. Yuliy, the Jaegers' most skilled warrior, is the sole survivor of a vampire raid on his home village. Drawing on the strength from his werewolf blood, he works with his team to assist Tokyo's law enforcement with the vampire crisis. Although they appear to be helping the police, the Jaegers are actually battling the vampires over the mystical Ark of Sirius. Possessing the power to alter the world's fate, the artifact must be found by Yuliy and his friends before the vampires can use it to achieve their destructive goals.