Seishuu Handa embodies everything a high school boy might aspire to be: handsome, intelligent, and a calligraphy prodigy. Despite being revered by the entire school, Handa remains entirely oblivious to his popularity. To the amusement of his best friend, Takao Kawafuji, Handa is convinced that his classmates' admiration is actually bullying. Unfortunately for him, every attempt he makes to avoid being "bullied" only results in another student, whether a model student or a delinquent, joining the ranks of Handa's worshippers. Handa-kun depicts the hilarious high school days of the young calligrapher and his ever-growing fanbase, even though all he desires is a quiet life.