Fudo Jun is a beautiful supermodel idolized by many. She also harbors a dark secret that she is initially unaware of, as her blood carries the genes for the next stage of human evolution. It is the same blood as the beast-like superhumans terrorizing the city. Unlike the others, however, Jun has managed to maintain a fragile hold on her humanity. She is recruited by the mysterious Asuka Ran, a member of a secret government organization dedicated to controlling, or if necessary eliminating, these berserk destroyers of mankind. As Devilman Lady, Jun must now exterminate her own kind, but how long can she preserve her sanity in a situation she never chose?