Following an interplanetary war at the start of the 21st century, Earth lies in ruins, with much of its ecosystem completely destroyed. Since normal life on the planet is no longer possible, inhabitants are forced to relocate to other worlds where life will, hopefully, be more comfortable. The Deep Galactic Trade Organization, a totalitarian regime governing many of these newly settled planets, has somehow concluded that music is a source of evil and must be banned and destroyed permanently. The talent group AKB0048 is soon formed, based on the original AKB48 members who once lived on Earth. Although their music is now considered universally illegal, they make it their mission to revive it by traveling from planet to planet and holding as many concerts as possible. They must undergo an entirely new set of training methods to become the best they can be, all while avoiding the constant danger of arrest for their musical activities. Join interplanetary pop stars AKB0048 as they try to save the world - with music!