Yu☆Gi☆Oh! Arc-V focuses on Yuuya Sakaki, a mysterious Entertainment Duelist known as "The Phantom," along with his three other personalities: Yuuto, Yuugo, and Yuuri. He was pursued by Leo Corporation for hacking into their Solid Vision with mass system and using it for his own purposes. While on the run, he meets Yuzu Hiiragi, the daughter of the principal of Syu Zo Duel School, which was on the verge of bankruptcy. She tricked Yuuya into a contract to become a teacher at her school. However, before Yuuya could teach at the school, he first had to find a card called Genesis Omega Dragon, which was said to determine the fate of the world and was also connected to his scattered memories. The story is set in an alternate version of Miami City, where Leo Corporation, run by its president Reiji Akaba, dominates most of the Solid Vision system throughout the city. The spread of the company's Solid Vision with mass not only gave birth to "Action Duels" but also helped improve the city by saving lives and repairing damage in case of disaster, becoming a vital part of people's lives.