Welcome to the Voynich Hotel, a dilapidated resort situated on a nearly deserted island in the South Pacific. Owned by former Mexican wrestler Kandre Umeda, the property is kept up by two enigmatic maids, Elena and Beluna, alongside a murderous chef named Amelia. Taizou Kuzuki, a Japanese tourist, arrives at the hotel to flee his dark past. He soon finds that the island's peculiar inhabitants and events are even more bizarre than what he is accustomed to. Taizou rapidly gets tangled in the island's web of affairs, forming bonds with several residents and assisting them, although this often creates further trouble for himself. However, when Taizou's past arrives on the island to haunt him, his new friends rush to his aid.