Asano is a diligent worker, yet he harbors a deeply ingrained smoking habit. Whether he claims to be swamped with work or simply has some free time, he is invariably seen with a cigarette in hand. Each time he smokes, Tabako-chan appears to keep him company; she is the anthropomorphized smoke emanating from his cigarette. Asano's fondness for smoking, combined with his dynamic relationship with Tabako-chan, leads the pair into various encounters and experiences with other smokers, each of whom has their own personified cigarette. Through their personified bonds with alluring smoke girls, Tabako-chan explores the unique and frustrating struggles faced by smoking addicts.