Debutante Detective Corps opens with introductions to the five main characters: Miyuki, Reika, Youko, Nina, and Kimiko. It appears that these five girls are extremely wealthy and have received a threatening video tape from unknown sources. A police guard is established at the school where the girls are enrolled. Kimiko, however, dislikes the idea of being confined to school and persuades the other girls to deceive the police into leaving. As soon as the police depart, the girls are attacked by three armed terrorists. What follows is a rather absurd adventure as the heroines attempt to foil their attackers.