Shiharu Nakamura is a high school student who adores children, resides in an orphanage, and dreams of opening a daycare. She holds a part-time job at a nursery school attended by the adorable two-year-old twins, Akane and Aoi Matsunaga. One day, a handsome young man named Seiji Matsunaga rushes to collect the twins, but they refuse to leave with him, clinging to Shiharu instead. Startled by the children's intense attachment to Shiharu, Seiji urgently asks her to babysit them, offering to pay double her current wages at the daycare. Shiharu realizes that this income will cover her living and tuition costs while also giving her the experience needed to achieve her dream. Love So Life chronicles Shiharu's joyful days as she falls in love with her makeshift family, and the twins' early childhood as they play, learn, and grow.