Knights is a shonen manga story about the squire Mistletien, known as 'Mist' for short. Set in a medieval world where the church and its representatives are burning people en masse on suspicion of witchcraft, Mist and his organization are opposing the church and the 'Saints' who continue the witch hunts. Mist is feared and hated by the villagers due to his appearance; he wears a mask to conceal himself and goes by the name 'The Black Knight.' He travels with Euphemia, a young girl who is as skilled at mixing potions and poisons as Mist is with a sword.