Jesus centers on a high-profile assassin who plans to fake his own death and lay low to evade the FBI and all the mafia's hitmen. He intends to live off the money he obtained from drugs he stole from the mafia. Somehow, his plan fails and he cannot retrieve those drugs because they somehow got concealed in a school's wall, blocked by a super-strong blackboard. He has no choice but to pose as a high school teacher to guard his stash. While he tries to pretend to be an ordinary citizen as much as possible, he often gets involved in cases dealing with crimes and criminals. Will his true identity get busted? How long can he tolerate living his life in a normal world?