Private detective Hazama Itsuru is hired by Professor Tani to investigate a theft of cyborg parts, which eventually leads him to meet Sachiko Yokogawa, the original 8 Man's love interest. Now working for Biotecho Corp., Sachiko finds herself involved with a new 8 Man who appears after Hazama is fatally wounded by an unknown cyborg. Against a violent urban backdrop where cyber-junkies create chaos across the city, this other 8 Man fights criminals in a more aggressive manner.