In contemporary Japan, Hyakki, an ancient swordsman, hunts youkai to recover the shards of his body stolen by demons. Roro, a homeless girl seeking revenge for her parents' murder, must also uncover the mystery of a shard hidden within her. Bound by fate, they team up to fight demonic enemies. This series expands on Osamu Tezuka's Dororo, bringing its story of vengeance and redemption into the modern era.