The narrative of Ciguatera centers on Ogino, who endures bullying in high school alongside his friend Takai. The pair find solace in their shared passion for motorcycles, hoping that acquiring one will inject some hope and vitality into their otherwise bleak existence. They are secretly taking driving lessons at a school, where Ogino's life begins to change permanently. The manga tracks a diverse cast of characters through their high school and working years, depicting their struggles, triumphs, dreams, futures, love, life, and loss. Ciguatera is a mature manga by Minoru Furuya, the author of Ping Pong Club and Himizu.