Invited to Nazi Germany during World War II, Dr. Asagumo is asked by Hitler to collaborate on the research of the new weapon "Big X". Concerned about the possible effects of completing Big X, Dr. Asagumo intentionally delays the research progress, conspiring with his co-researcher, the devious Dr. Engel. Immediately before Germany is defeated by the Allies, Dr. Asagumo implants a card inscribed with the secret of Big X into his son, Shigeru, and is then shot to death by the German army. Twenty years later, the card is discovered in the body of Shigeru, who is then living in Tokyo. Soon, an organization claiming alliance with the Nazis appears, steals the card, and completes the Big X project. Dr. Engel's grandson has joined the Nazi Alliance. The completed Big X is then revealed to be a drug that can expand the human body without limitation. Recovering Big X from the enemy, Shigeru's son Akira fearlessly challenges the Nazi Alliance and Hans Engel, who are plotting to conquer the world.