Seventeen years ago, mysterious immortal soldiers known as divine warriors appeared on the battlefields of Africa. These life forms later became known as Ajin, or demi-humans, and were considered to be one of mankind's greatest discoveries. The government declared their existence compatible with humans; however, rumors suggest that they instead offer bounties for captured Ajin to secretly conduct inhumane experiments on these rare beings. Kei Nagai, an apathetic high school student, is studying to become a doctor and only wishes to live a normal life. However, this simple dream is shattered after he is suddenly involved in a deadly traffic accident. Revived at the scene, he is immediately labeled as an Ajin by witnesses seeking the bounty. Unable to understand his immortality or prove his innocence, he begins living on the run and fighting for survival. He barely escapes the government's reach when a group of anarchistic Ajin contacts Kei, asking him to join their forces to retaliate against the government. But who is Kei's real enemy, and which side will he take when it comes down to humans versus Ajin?