Gilliam was the scientist who created the Bioroids, as well as the "D-tank" virus, which is capable of rendering normal humans sterile. It was during the creation of the first generation that she realized the Council of Elders planned to use the Bioroids to replace normal humanity altogether, with normal humans rendered sterile by the "D-tank" virus. Therefore, she arranged for the Bioroids to be unable to reproduce, but she kept and encoded the formula to activate their reproductive systems—codenamed "Appleseed"—in a pendant. After having her assistant Athena evacuated, she gave the pendant to her young daughter Deunan, with the promise to give it to Athena if she asked. Gilliam is captured and inadvertently killed by a soldier in front of Deunan.
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