Kamineko (meaning "Biting Cat" in Japanese) is an adorable gray cat that Sakaki occasionally encounters on her commute to and from school. Because Sakaki has a deep affection for cats, she attempts to pet it, but the cat ends up clamping its massive, bear-trap-like teeth onto her hand. This incident has become one of the series' most prominent running gags. Kamineko appears to hold a strong grudge against Sakaki, and at one point, it even tries to mobilize all the cats in the neighborhood to attack her. Meanwhile, Tomo has somehow acquired a plush toy version of Kamineko, which also features bear-trap teeth.
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